SYRACUSE -- In a tightly-contested league race, the Lancers could not afford a misstep against defending state 5-A champion Syracuse High.
Despite kissing off a nine-point second-quarter lead Friday and committing a turnover with 22.8 seconds remaining while holding a three-point edge, Layton dribbled the final 1.9 seconds off the clock after the Titans threw the ball away on an ill-advised cross-court pass.
Final score: Layton 50, Syracuse 49.
"This win was really big and we wanted to beat them," said Lancers junior shooting guard Cassidy Anderson. "We hadn't beaten them in four years."
Layton, which last won a Region 1 girls basketball title during the 2005-06 season when it was co-champion with Clearfield, remained in a first-place tie with Davis.
The Lancers (12-4 overall, 4-1 league) defeated four-time defending league champion Syracuse for the first time since a 55-51 road breakthrough on Feb. 6, 2009.
"I can live with being 4-1 in region," said the 16-year-old Anderson. "We have to play it one game at a time. We still have to play every game and there are five left.
"If we play together, we're good enough to win region," she said. "We played our pace and we played as a team today. We didn't play as a team against Davis (a 52-41 road setback on Jan. 18). We got back on track today."
Anderson tied her career high of 14 points, going 5 of 8 from the floor, including 3 of 5 from 3-point range. She had one rebound, five assists and two steals for Layton, which is 5-3 in its last eight games.
"I was just trying to help our team win," Anderson said. "I took advantage of what the defense gave me. I think when we get a lead we lose focus and become lackadaisical. We need to get our heads back in those situations."
Maddi Smith scored 13 points on 4-of-10 shooting with six boards, three assists and one steal for the Lancers, who shot 47.5 percent (19 of 40) -- 44.4 percent (4 of 9) from deep -- and got outrebounded 26-19.
Jaden Anderson had eight points, two boards and two assists and Livia Treseder had six points, eight rebounds and two steals for Layton, which committed 19 turnovers with 17 assists and 11 steals.
The Lancers converted 7-of-10 fourth-quarter free throws.
Syracuse (6-9, 2-3) had its two-game winning streak snapped and is just 3-7 in its last 10.
Paige Trimble scored a team-high 12 points on 4-of-6 shooting. Jayda Bovero went 5 of 13 from the floor for 11 points with three rebounds, one assist, a steal and one block for the Titans, who shot 45.2 percent (19 of 42) and were 0 of 6 on 3-point attempts.
Takenna Hamblin had 10 points, five boards and three steals for Syracuse, which committed 18 turnovers with eight assists and nine steals.
Courtney Starks, playing in only her third game after knee surgery, had six points, nine rebounds, three assists and five steals.
"Having a week off helped us prepare for them and get our plays down," Cassidy said. "We focused during the week on controlling the tempo, playing our game and not being in such a rush offensively."
* WEBER 52, NORTHRIDGE 26: At Pleasant View, Erin Reichle scored 22 points and the Warriors doubled up the Knights in a rout.
Hannah Charlton chipped in eight points for the Warriors.
Sydnee Acord had a team-high 14 points for Northridge in the loss.
* DAVIS 39, FREMONT 36: At Kaysville, Jessica Richardson tied for a game-high 16 points and the Darts played a tough fourth quarter to narrowly defeat Region 1 rival Fremont.
Natalie Mecham had 13 points and nine rebounds for Davis in the win.
Shelby Molen led the Silver Wolves with 16 points on four 3-pointers, while Amanda Wayment added 13 in the loss.
* CYPRUS 64, CLEARFIELD 58: At Magna, the Pirates held off the Falcons in a hotly-contested battle.
Jocelyn Jones paced Clearfield with 21 points and Bailey Douglas scored 11 in the defeat.
In another league game, Bountiful started fast and held on for a 59-42 win over Woods Cross at home. The Braves led 34-9 at halftime.
Tiana Dougher led the Braves with a game-high 13 points. Aubree Riddle paced the Wildcats with 11 points.